Python Job: Computational Scientist - Single Cell Genomics

The Computational Biology group in Garvan’s Data Science Platform focuses on genomics and biomedical data analysis, combining computational skills with biological domain expertise. The group applies and develops computational methods to better understand human disease. We take a collaborative approach, working closely with experimental and clinical researchers to tackle problems that address critical unmet medical needs.

THE OPPORTUNITY

We are looking for a Computational Scientist with experience in analysing single cell data. Successful candidates will work on genomics studies with experimental and clinical researchers across Strategic Programs at Garvan. Projects include single cell and spatial transcriptomic studies of cancer and genetic diseases, using clinical samples or animal models. Successful candidates will contribute to all study stages, including design and planning, data analysis, interpretation and manuscript writing.

Salary: Negotiable dependent on experience
Employment Type: 2 year maximum term contract

SNAPSHOT OF BENEFITS

• Generous salary packaging to save you income tax on your wages thereby boosting your monthly take home pay (max. $15,900 general expenses + $2,650 meals/accom)

• Ample opportunities for on-going training and development

• Stimulating, diverse and highly international research environment

• Flexible work arrangements e.g. location, start / finish times etc

• 18 weeks paid parental leave for both parents including paid superannuation

• A range of additional leave types to meet your personal needs including cultural leave, conference leave, community service and study leave

• Discounted Health Insurance

• Lifestyle discounts with our community partners

WHAT YOU WILL DO

The key responsibilities include:

• Analysis of high-throughput datasets, including quality control, unsupervised and supervised analyses, with emphasis on biological interpretation

• Preparing figures for publication, contributing to manuscript writing

• Experimental design and planning

• Creating and maintaining modular and reusable workflows through use of container and workflow management technologies

• Developing best practices for computational workflows through evaluation/benchmarking of existing methods and/or original method development

• Staying informed on advances in computational methods, genomics, as well as building and maintaining biological domain expertise

• Contribute to internal education programs through designing and running workshops, mentoring, technical supervision, code reviews

ABOUT YOU

The key skills and experience include:

• PhD degree in a related area of science or engineering or equivalent experience

• Good statistical knowledge and programming skills

• Good knowledge of biology

• Previous experience working with next-generation sequencing data, such as single-cell sequencing, spatial transcriptomics, RNA-seq, targeted or whole-genome sequencing, ChIP-seq, ATAC-seq

• Publications commensurate with experience

• Comfortable working with Unix and in an HPC environment

• Proficient in at least one scripting language (R, Python)

• Familiar with version control systems

• Experience with software containers, workflow management systems, databases, cloud computing

• Highly developed written and verbal communications skills

ABOUT GARVAN

The Garvan Institute of Medical Research is an independent Medical Research Institute (MRI) in Sydney, delivering scientific and clinical impact on a global basis and in partnership with organisations that share our vision. We are proud to be one of Australia’s largest and most highly regarded MRIs.

Our vision is global leadership in discoveries to impact and our enduring purpose is to impact human health, by harnessing information encoded in our genome.

We seek to see our world-class discovery research achieve life-changing impacts, not only for individual patients with rare diseases, but for the many thousands affected by complex, common disease.

Garvan promotes a diverse workplace and is committed to the principles of equity, diversity, inclusion and belonging.

HOW TO APPLY

To apply for this position, please submit your application with a CV and cover letter as one document, stating why you are interested in this role. We are reviewing applications as they are received.

Job Type: Full-time

Salary: Up to $15,900.00 per month